Vaping has quickly transitioned from a supposed “healthier” smoking alternative to a public health concern in its own right. Over the past decade, e-cigarettes have exploded in popularity—especially among young people—driven by sleek marketing, an endless variety of flavors, and the illusion of safety.
But beneath the fruity flavors and clouds of vapor lies a threat that most users never see coming: Popcorn lung—a severe, irreversible lung disease linked to the chemicals found in flavored vape products.
With hundreds of different chemicals in circulation, many of which have not been adequately tested for inhalation safety, experts are sounding the alarm. This article explores what popcorn lung is, how vaping contributes to it, the science behind the chemicals involved, and why experts now insist that prevention—not treatment—is the only viable strategy.
What is Popcorn Lung? A Closer Look

Popcorn lung, known in medical terms as bronchiolitis obliterans, is an uncommon yet severe disorder that harms the smallest passages in the lungs, called bronchioles. These airways become inflamed and scarred, which thickens and narrows them, making it increasingly difficult for air to pass through.
Unlike asthma or infections, which may cause temporary airway constriction, popcorn lung results in permanent scarring and tissue damage. The name originates from a cluster of cases in microwave popcorn factory workers in the early 2000s who developed this condition after inhaling high levels of a chemical called diacetyl used in butter flavoring.
Common Symptoms of Popcorn Lung:
- Shortness of breath (especially after exertion)
- Dry, persistent coughing
- Wheezing or crackling sounds in the chest
- Fatigue
- Chest tightness
These signs frequently resemble those of other lung conditions, which can make prompt identification challenging.